As much as we love our furry friends, we cannot deny the fact that fleas and ticks can cause serious harm to them. These pesky parasites not only cause skin irritation but can also spread deadly diseases to your pets. It is therefore essential to give them the best protection against these pests by choosing the most reliable and effective treatment.
Among many treatments available in the market, Nexgard Chewables For Large Dogs stands out as a popular and trusted solution for protecting your pooch against flea and tick infestations. In this blog, we will discuss why Nexgard Chewables For Large Dogs is considered as the best dog flea and tick medication on the market.
Nexgard Chewables For Large Dogs – Full Evaluation And Also Buying Guide
Check out our top products that you can purchase:
*Note: The score is based on our AI score (Editor’s choice and rating).
NexGard® (afoxolaner) Flea and Tick Protection for Dogs Oral Soft Beef Flavored Chewables, 24.1 to 60 lbs. (Purple Box) 1 Chew (1 Month Supply)
$34.69
in stock
Amazon.com
as of August 12, 2025 7:28 am
Features
- #1 vet-recommended flea and tick control that kills fleas fast, before they can lay eggs.¹
- This flea and tick treatment product is FDA-approved to prevent Lyme infections as a direct result of killing black-legged ticks.
- Kills fleas and ticks all month long.
- #1-preferred by dogs.² Each NexGard (afoxolaner) flea and tick chewable is easy to give because dogs love the delicious beef flavor.³
- Safe for dogs and puppies as young as 8 weeks, weighing 4 pounds or more.
NexGard Plus (afoxolaner, moxidectin, and pyrantel) Flea and Tick Protection & Heartworm Preventive for Dogs Soft Beef Flavored Chewables, 8.1-17 lbs. (Green) 3 Chews (3 Month Supply)
$111.89
in stock
Amazon.com
as of August 12, 2025 7:28 am
Features
- Convenient one-and-done monthly dosing for parasite protection for dogs
- Provides flea and tick protection for dogs
- Kills adult fleas and 5 species of ticks
- Effective prevention of heartworm disease
- Treats and controls 3 species of hookworms and 2 species of roundworms
Advantus Dog Fast Acting Oral Flea Treatment Soft Chews Dogs 23 - 110 lbs. | 7 ct.
$32.18
out of stock
3 new from $32.11
Free shipping
Amazon.com
as of August 12, 2025 7:28 am
Features
- Advantus (imidacloprid) is a flavored soft chew that, with one dose, starts killing adult fleas within one hour so your dog can get back to enjoying life
- This chewable flea treatment is available without a prescription
- Treats flea infestations on dogs and puppies 10 weeks of age and older and weighing from 23 - 110 lbs.
- Easy-to-give soft chew that can be administered to your dog as often as once daily if they become re-infested
- Advantus is also available for dogs ranging in weight between 4 and 22 lbs.
HEARTGARD® Plus (ivermectin/pyrantel) Real-Beef Chewables for Dogs up to 25 lbs (Blue Box) 6 Month Supply of Chews (Heartworm Disease Preventive)
$56.49
in stock
Amazon.com
as of August 12, 2025 7:28 am
Features
- Vet-recommended heartworm preventive
- Effectively prevents heartworm disease
- Also treats and controls roundworms & hookworms
- From the brand trusted over 2.5 billion times
- Delicious once a month real-beef chew that dogs love
TevraPet Activate II Flea and Tick Prevention for Dogs | 4 Count | Extra Large Dogs 55+ lbs | Topical Drops | 4 Months Flea Treatment
$26.97
in stock
Amazon.com
as of August 12, 2025 7:28 am
Features
- COMPARE TO K9 ADVANTIX II: Activate II uses Imidacloprid, Permethrin, and Pyriproxyfen - the same safe, fast acting active ingredients used in Advantix II for Dogs. Includes 4 monthly doses
- ACTIVELY PROTECTS YOUR DOG: Activate II is approved by veterinarians to repel and kill fleas and ticks on contact - before your dog is exposed to bites and potential flea borne illnesses
- STOP INFESTATIONS FAST: Our topical drops prevent infestations by breaking the flea life cycle - our insect growth regulator (IGR) starts killing flea eggs and larvae within 12 hours of application
- EASY TO APPLY: Simply apply to the base of your dog's neck, and the waterproof solution will travel across the skin - providing continuous protection for 30 days per application
- MADE IN AMERICA - RESULTS GUARANTEED: TevraPet Activate II is made to the quality standard we demand for our own pets. We're proud to help you protect your dog with confidence
PetArmor Plus Flea and Tick Prevention for Dogs, Dog Flea and Tick Treatment, 6 Doses, Waterproof Topical, Fast Acting, Large Dogs Dogs (45-88 lbs)
$39.98 in stock
3 new from $39.98
Free shipping
Amazon.com
as of August 12, 2025 7:28 am
Features
- EFFECTIVE, WATERPROOF FLEA TREATMENT FOR DOGS: PetArmor Plus is a waterproof, flea & tick topical prevention for dogs that kills fleas, flea eggs, flea larvae, ticks, and chewing lice for up to 30 days after application.
- TRUSTED, VET QUALITY FORMULA: Containing fipronil and (S)-methoprene, the same active ingredients as FRONTLINE Plus for Dogs. PetArmor Plus for Dogs has a powerful formula that starts to kill fleas within 24 hours.
- BREAK THE FLEA CYCLE: Unlike other flea and tick treatments that may temporarily suppress flea activity, PETARMOR Plus Dog Flea Treatment works by effectively breaking the flea life cycle. Kill flea eggs and larvae to prevent re-infestation.
- FAST ACTNG LONG-LASTING FLEA AND TICK PROTECTION: One application of PetArmor Plus lasts up to 30 days nose to tail. A 6-dose package lasts up to six months.
- EASY-TO-USE, LONG-LASTING: PetArmor Plus flea and tick treatment comes with six (6) waterproof topical applications that provide your pet flea protection and control for (6) months.
Capstar(nitenpyram) for Dogs Fast-Acting Oral Flea Treatment for Dogs 2-25 lbs, Vet-Recommended Medication Tablets Start Killing in 30 Minutes, 6 Doses
$38.12 in stock
4 new from $38.12
Free shipping
Amazon.com
as of August 12, 2025 7:28 am
Features
- Fast-Acting Flea Treatment: CAPSTAR (nitenpyram) starts killing adult fleas in just 30 minutes
- Tackle Flea Infestations Fast: With one dose of CAPSTAR, you can watch the dead fleas fall off your pet
- Treat Reinfestations Fast: If your pet gets reinfested with fleas, simply give another dose as often as once a day
- No Prescription Needed: Fast, effective flea treatment for dogs that's available over the counter
- Intended Use: CAPSTAR Oral Flea Treatment for Small Dogs (57 mg) is safe for dogs and puppies 4 weeks and older that weigh 2-25 pounds
1. Kills Fleas and Ticks Quickly
Nexgard Chewables For Large Dogs is a beef-flavored chewable tablet that can be easily given to your dog once a month. What makes it so effective is its active ingredient Afoxolaner which starts killing fleas in just four hours and ticks in eight hours. This fast-acting formula can give your dog instant relief from fleas and ticks infestations.
2. Protection Lasts for a Month
Nexgard Chewables For Large Dogs ’s protection lasts for a month, making it a convenient option for pet owners. Unlike other treatments that need to be applied frequently, a single dose of Nexgard Chewables For Large Dogs is sufficient for eliminating and preventing flea and tick infestations.
3. Safe for Dogs of All Sizes
Nexgard Chewables For Large Dogs is safe to use for dogs of all sizes and breeds. It is available in various strength levels that can cater to different weight ranges of dogs. This flexibility makes it a popular choice among veterinarians and pet owners.
4. Easy to Administer
Giving medicine to pets can be a harrowing task, but not anymore with Nexgard Chewables For Large Dogs . The chewable format of this medication is easy to administer and is readily taken by dogs. It can even be administered with or without food, making it ideal for picky eaters.
5. Minimal Side Effects
Nexgard Chewables For Large Dogs has minimal side effects, making it a suitable option for dogs with pre-existing medical conditions. As with any medication, some dogs may experience mild side effects such as vomiting, diarrhea, or lethargy. However, these side effects are not serious and usually subside within a day or two.
Conclusion:
Flea and tick infestations can cause a great deal of discomfort to our pets and can also lead to serious health threats. Nexgard Chewables For Large Dogs is considered the best dog flea and tick medication on the market because of its fast-acting formula, long-lasting protection, safety for pets of all sizes, easy administration, and minimal side effects.
As a pet owner, it’s important to choose the best solution to protect your furry friend against these pests. Talk to your veterinarian about Nexgard Chewables For Large Dogs today and give your pooch the best protection they deserve.
